Obstructive sleep apnea is characterized by the repetitive collapse of the
upper airway during sleep. A variety of nonsurgical treatments for obstruct
ive sleep apnea have been developed, including behavioral therapies, contin
uous positive airway pressure (CPAP) devices, oral appliances and medicatio
ns. Presently, CPAP is considered the first-line treatment for moderate to
severe sleep apnea and one of the first-line treatments for mild disease. H
owever, the effectiveness of CPAP is compromised because a large proportion
of patients cannot tolerate the devices. Oral appliances are one of the fi
rst-line therapies for mild sleep apnea and a treatment for more severe dis
ease if CPAP cannot be tolerated. Medications have thus far been unsuccessf
ul as a treatment option for sleep apnea. Ail patients should be counseled
to avoid sleep deprivation and sedatives (including alcohol) and to lose we
ight if obese. (C) 1999 Prous Science. Ail rights reserved.