New approaches in the management of patients with chronic congestive heartfailure

Citation
M. Jessup et S. Brozena, New approaches in the management of patients with chronic congestive heartfailure, DRUGS TODAY, 35(11), 1999, pp. 849-855
Citations number
44
Categorie Soggetti
Pharmacology
Journal title
DRUGS OF TODAY
ISSN journal
00257656 → ACNP
Volume
35
Issue
11
Year of publication
1999
Pages
849 - 855
Database
ISI
SICI code
0025-7656(199911)35:11<849:NAITMO>2.0.ZU;2-L
Abstract
The cost of caring for a growing number of patients with congestive heart f ailure is a staggering economic burden. Fortunately, an increasing number o f evidence-based guidelines have been developed which, if implemented, have the potential to save lives and money. In addition, there are newer unders tandings about the potential of current therapies, both medical and surgica l, to prevent the progression of disease. The foundation of diuretics, ACE inhibitors and beta-blockers serves to improve symptoms, decrease hospitali zations and improve survival. The roles of angiotensin receptor antagonists and cytokine antagonists are currently being clarified. The potential for myocardial recovery during left ventricular assist implantation has paved t he way for some exciting surgical procedures. The challenge in the future w ill be to develop an approach to the patient with heart failure which takes advantage of this new knowledge while avoiding a bewildering array of cost ly drugs which may not all be necessary at all stages of the disease. (C) 1 999 Prous Science. All rights reserved.