Standard preoperative assessment can improve outcome after cholecystectomy

Objective: To assess the outcome of cholecystectomy after standard preopera tive handling and selection of patients, focusing on the potential of the o peration to eliminate biliary colic. Design: Prospective study. Setting: University Hospital, Norway. Patients: 806 patients (median age 56, range 18-91 years, male:female ratio 1:2.7), were referred to our clinic for cholecystectomy between 1992 and 1 996. Interventions: Unless there was a clear indication for cholecystectomy (fre quent attacks of biliary colic/or recent complications of gallstones or bot h), patients were investigated in a standard way to find out what else was causing the abdominal pain. Main outcome measures: Residual pain was assessed at a clinical examination three months postoperatively, and clinical condition a median of three yea rs later was assessed by a questionnaire. Results: 465 (58%) patients were operated on primarily, and an additional 2 9 patients were operated on after further evaluation. Three months after ch olecystectomy, 35 (7%) had persistent pain, mostly caused by other specific diseases and relieved after specific treatment. A median 3 years postopera tively, only 21 (4%) reported that they still had abdominal pain. Conclusion: Standard selection of patient improved the outcome of cholecyst ectomy. Compared with a historical control group, residual pain after three months was reduced from 20% to 7%. After three years, 96% of the patients no longer had their main clinical problem.