Recurrent venous thrombosis in a patient with chronic lymphocytic leukemiaand acquired protein S deficiency

Authors
Miljic, P Milosevic-Jovicic, N Antunovic, P Boskovic, D Basara, N Rolovic, Z
Citation
P. Miljic et al., Recurrent venous thrombosis in a patient with chronic lymphocytic leukemiaand acquired protein S deficiency, HAEMATOLOGI, 30(1), 2000, pp. 51-54
Citations number
9
Categorie Soggetti
Hematology
Journal title
HAEMATOLOGIA
ISSN journal
00176559 → ACNP
Volume
30
Issue
1
Year of publication
2000
Pages
51 - 54
Database
ISI
SICI code
0017-6559(2000)30:1<51:RVTIAP>2.0.ZU;2-H
Abstract
A patient with chronic lymphocytic leukemia and an undetectable plasma leve l of protein S (PS), associated with recurrent venous thrombosis, is descri bed. The laboratory investigation revealed the concomitant presence of an i nhibitor directed to PS and a monoclonal protein in the patient's plasma. A fter treatment with prednisone and cyclophosphamide both the inhibitor to P S and the monoclonal component disappeared.