Hyperkeratosis lenticularis perstans (Flegel's disease) - a complex disorder of epidermal differentiation with good response to a synthetic vitamin D3 derivate

Authors
Metze, D Lubke, D Luger, T
Citation
D. Metze et al., Hyperkeratosis lenticularis perstans (Flegel's disease) - a complex disorder of epidermal differentiation with good response to a synthetic vitamin D3 derivate, HAUTARZT, 51(1), 2000, pp. 31-35
Citations number
19
Categorie Soggetti
Dermatology
Journal title
HAUTARZT
ISSN journal
00178470 → ACNP
Volume
51
Issue
1
Year of publication
2000
Pages
31 - 35
Database
ISI
SICI code
0017-8470(200001)51:1<31:HLP(D->2.0.ZU;2-Y
Abstract
Hyperkeratosis lenticularis perstans (Flegel's disease) is a rare but clini cally and histologically highly characteristic genodermatosis. We report on new immunohistochemical and ultrastructural findings suggesting a complex disorder of epidermal differentiation. In this context, a good response to calcipotriol, a synthetic vitamin D3 derivative is of particular interest.