This study was conducted to investigate the apparent precaecal digestibilit
ies of niacin and pantothenic acid from human nutrient related foods includ
ing wheat, coarse whole-meal bread, boiled potatoes and boiled pork and bee
f. Therefore, pigs were subjected to an end-to-end ileo-rectal anastomosis,
so digesta passed straight from ileum to rectum. eliminating endogenous vi
tamin synthesis. Excreted chyme was collected over 5-days periods, and conc
entrations of niacin. and pantothenic acid in the food and chyme samples we
re determined microbiologically. The intestinal bioavailability of niacin a
nd pantothenic acid was affected differently by the food administered. The
digestibility values of niacin deriving from the wheat-, potato- and the nl
c ut-based meals ranged from 59 to 69%. Wholemeal bread exerted a nutrition
ally important negative effect on the apparent intestinal availability of d
ietary niacin relative to the other foods. which averaged by 40%. Food-rela
ted differences of the pantothenic acid digestibility values were greater t
han that observed with niacin. The digestibility values of pantothenic acid
from wheat, potatoes and the meat meals ranged between 65 and 81% and were
of the order wheat diet > pork diet > potato diet > beef diet, although di
fferences were not statistically significant. The digestibility of pantothe
nic acid from the coarse wholemeal bread diet was lower than 30%.