The psychometric properties of the Beck Depression Inventory (BDI) in subje
cts with Alzheimer's disease (AD) and depression have not been fully evalua
ted. Item endorsement patterns may be distorted by the presence of AD. This
was tested by applying the BDI to a sample of 129 subjects with probable A
D without depression and to 57 subjects with both probable AD and depressio
n. It was found that the BDI under diagnoses depression in the context of A
D. ROC curves for total BDI and cognitive and somatic items subsets showed
low sensitivity and low areas under the curve indices. The results suggest
that the BDI is not an ideal instrument to measure depression in AD. This m
ay not result solely from the swing of the somatic items subset, but from o
ther aspects which require further investigation. Copyright (C) 2000 John W
iley & Sons, Ltd.