Polyglyceryl oleates with 3,6,10 glycerol groups formed lamellar liquid cry
stal with water. The penetration of water into amphiphilic bilayer was redu
ced with increased the number of glycerol groups. Polyglyceryl oleate enter
ed into a liquid crystalline model of the stratum corneum lipids reduced th
e penetration of water and enhanced the stability towards low water content
.