Unusual presentation of a Merkel cell carcinoma

Citation
Tg. Chiarelli et al., Unusual presentation of a Merkel cell carcinoma, J AM ACAD D, 42(2), 2000, pp. 366-370
Citations number
41
Categorie Soggetti
Dermatology,"da verificare
Journal title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN journal
01909622 → ACNP
Volume
42
Issue
2
Year of publication
2000
Part
2
Supplement
S
Pages
366 - 370
Database
ISI
SICI code
0190-9622(200002)42:2<366:UPOAMC>2.0.ZU;2-3
Abstract
Merkel cell carcinoma (MCC) is an uncommon, potentially lethal, cutaneous t umor that mainly occurs in sun-exposed skin of the head and neck area of th e elderly. We report a case of MCC presenting as a 2-mm crusted erosion on the nose of an elderly patient, the smallest MCC reported thus far in the l iterature. The optimal management of MCC has not been clearly established. In view of its high local recurrence rate, predilection to metastasis, and significant mortality, aggressive treatment has been advocated. Identificat ion of this tumor at such a small size posed a management dilemma because o f lack of prospective treatment data involving biologic markers of prognost ic significance for MCC.