The MR imaging-based assessment of the optic nerve in optic neuritis and mu
ltiple sclerosis provides information that is complementary to clinical and
electrophysiological methods. The standard and more tissue destruction spe
cific methods can be used in strategies to measure treatment efficacy and f
or understanding the mechanisms of relapse, recovery, and failure of recove
ry. (C) 2000 Elsevier Science B.V. All rights reserved.