Phenotypic expression of Lp(a) in Spanish children and adolescents

Authors
Gerique, JAG Martinez, DL Cancelas, P Montoya, MT Gutierrez, MD Porres, A
Citation
Jag. Gerique et al., Phenotypic expression of Lp(a) in Spanish children and adolescents, MED CLIN, 114(1), 2000, pp. 13-15
Citations number
10
Categorie Soggetti
General & Internal Medicine
Journal title
MEDICINA CLINICA
ISSN journal
00257753 → ACNP
Volume
114
Issue
1
Year of publication
2000
Pages
13 - 15
Database
ISI
SICI code
0025-7753(20000115)114:1<13:PEOLIS>2.0.ZU;2-T
Abstract
BACKGROUND: To know the distribution of phenotypes Lp(a) in an young popula tion. METHODS: Lipoprotein levels, lipoprotein(a), apolipoproteins and the Lp(a) phenotypes were determinated in 105 children, selected according to their c holesterol concentrations. RESULTS: The Lp(a) concentrations were significantly higher in group with l ow molecular weight respect to group with high molecular weight. The most f requent isoform was S3. CONCLUSIONS: The Lp(a) concentrations correlate inversely with the molecula r weight of Apo(a) isoforms.