Purpose: The purpose of this study was to evaluate the potential associatio
n of muscular strength and endurance at baseline with the prevalence of fun
ctional limitations at follow-up. Methods: Study participants were 3,069 me
n and 589 women (30-52 yr) who received a clinical examination including a
strength evaluation at the Cooper Clinic between 1980 and 1989 and responde
d to a 1930 mail-back survey. Participants also had to achieve at least 85%
of their age-predicted maximal heart rate on a maximal exercise treadmill
test and have no history of heart attack, stroke, diabetes, high blood pres
sure, cancer, or arthritis at their first visit. A strength index composite
score (0-6) was calculated using age- and sex-specific tertiles from bench
press, leg press, and sit-up tests. Those scoring 5 or 6 were categorized
in the high strength group. Functional health status was assessed by respon
ses to questions about the participant's ability to perform light, moderate
, and strenuous recreational, household, daily living, and personal care ta
sks. Results: After an average follow-up of 5 yr, 7% of men and 12% of wome
n reported at least one functional limitation. A logistic regression model
including age, aerobic fitness, body mass index, and new health problems at
follow-up found that, relative to those with lower levels of strength, the
odds of reporting functional limitations at follow-up in men and women cat
egorized as having higher levels of strength were 0.56 (95%CI = 0.34, 0.93)
and 0.54 (95%CI = 0.21,1.39), respectively. Conclusions: These findings, i
f replicated in other populations, suggest that maintenance of strength thr
oughout the lifespan may reduce the prevalence of functional limitations.