Regioselective bromination of organic substrates by tetrabutylammonium bromide promoted by V2O5-H2O2: An environmentally favorable synthetic protocol

Authors
Bora, U Bose, G Chaudhuri, MK Dhar, SS Gopinath, R Khan, AT Patel, BK
Citation
U. Bora et al., Regioselective bromination of organic substrates by tetrabutylammonium bromide promoted by V2O5-H2O2: An environmentally favorable synthetic protocol, ORG LETT, 2(3), 2000, pp. 247-249
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
3
Year of publication
2000
Pages
247 - 249
Database
ISI
SICI code
1523-7060(20000210)2:3<247:RBOOSB>2.0.ZU;2-5
Abstract
[GRAPHICS] Vanadium pentoxide very effectively promotes the bromination of organic sub strates, including selective bromination of some aromatics, by tetrabutylam monium bromide in the presence of hydrogen peroxide; mild conditions, high selectivity, yield, and reaction rate, and redundancy of bromine and hydrob romic acid are some of the major advantages of the synthetic protocol.