Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization

Authors
Cinel, B Roberge, M Behrisch, H van Ofwegen, L Castro, CB Andersen, RJ
Citation
B. Cinel et al., Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization, ORG LETT, 2(3), 2000, pp. 257-260
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
3
Year of publication
2000
Pages
257 - 260
Database
ISI
SICI code
1523-7060(20000210)2:3<257:ADFECT>2.0.ZU;2-E
Abstract
[GRAPHICS] Six new antimitotic diterpenes, 2-7, have been isolated from the Caribbean octocoral Erythropodium caribaeorum, Structural variations encountered in t his group of natural products test recently proposed pharmacophore models f or microtubule stabilizing compounds.