Concerted catalytic reactions for conversion of ketones or enol acetates to chiral acetates

Citation
Hm. Jung et al., Concerted catalytic reactions for conversion of ketones or enol acetates to chiral acetates, ORG LETT, 2(3), 2000, pp. 409-411
Citations number
39
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
3
Year of publication
2000
Pages
409 - 411
Database
ISI
SICI code
1523-7060(20000210)2:3<409:CCRFCO>2.0.ZU;2-Q
Abstract
[GRAPHICS] Enol acetates or ketones asymmetrically transformed to chiral acetates in h igh yields with high optical purities through multistep reactions catalyzed by a lipase and a ruthenium complex. 2,6-Dimethylheptan-4-ol was chosen as a suitable hydrogen donor, and 4-chlorophenyl acetate was used as an acyl donor for the conversion of ketones.