Antiretroviral therapy of HIV infection in children

Knowledge concerning the pathogenesis of HIV infection and its clinical man agement has evolved rapidly since the global emergence of this infection in the human population 2 decades ago. This article focuses on the pathogenet ic features of pediatric HIV infection that affect therapy and decision mak ing, on the antiretroviral drugs available for children and current approac hes to their use, and on some therapeutic options that may be available in the near future.