Mo. Yenidunya et S. Yenidunya, Initially alloperfused autograft: An experimental study with rat groin free flap, PLAS R SURG, 105(2), 2000, pp. 648-653
The purpose of this experimental study was to investigate the effects of al
loperfusion on autografts. The authors designed an experimental model to st
udy flap viability during and after alloperfusion. They performed 23 free g
roin flap transfers on 46 rats. The flap was transferred as an autograft; h
owever, the anastomosis was performed as an allograft procedure. After the
operation, animals were held together on a table for observation. The rats
were randomly divided into two groups depending on whether or not a steroid
was given. They were fed by hand. At the end of the various waiting period
s, the pedicles were divided, and animals were separated from each other. T
he survival of the flap and the animal was observed. No flaps survived in t
he untreated group. Seven flaps in the steroid-treated group that had their
connections cut before 140 hours also did not survive. Five flaps that had
their pedicles cut after 140 hours survived. Results are presented and dis
cussed.