Initially alloperfused autograft: An experimental study with rat groin free flap

Citation
Mo. Yenidunya et S. Yenidunya, Initially alloperfused autograft: An experimental study with rat groin free flap, PLAS R SURG, 105(2), 2000, pp. 648-653
Citations number
9
Categorie Soggetti
Surgery,"Medical Research Diagnosis & Treatment
Journal title
PLASTIC AND RECONSTRUCTIVE SURGERY
ISSN journal
00321052 → ACNP
Volume
105
Issue
2
Year of publication
2000
Pages
648 - 653
Database
ISI
SICI code
0032-1052(200002)105:2<648:IAAAES>2.0.ZU;2-1
Abstract
The purpose of this experimental study was to investigate the effects of al loperfusion on autografts. The authors designed an experimental model to st udy flap viability during and after alloperfusion. They performed 23 free g roin flap transfers on 46 rats. The flap was transferred as an autograft; h owever, the anastomosis was performed as an allograft procedure. After the operation, animals were held together on a table for observation. The rats were randomly divided into two groups depending on whether or not a steroid was given. They were fed by hand. At the end of the various waiting period s, the pedicles were divided, and animals were separated from each other. T he survival of the flap and the animal was observed. No flaps survived in t he untreated group. Seven flaps in the steroid-treated group that had their connections cut before 140 hours also did not survive. Five flaps that had their pedicles cut after 140 hours survived. Results are presented and dis cussed.