Electrospray multistep ion trap mass spectrometry for the structural characterisation of poly[(R,S)-3-hydroxybutanoic acid] containing a beta-lactam end group

Authors
Adamus, G Kowalczuk, M
Citation
G. Adamus et M. Kowalczuk, Electrospray multistep ion trap mass spectrometry for the structural characterisation of poly[(R,S)-3-hydroxybutanoic acid] containing a beta-lactam end group, RAP C MASS, 14(4), 2000, pp. 195-202
Citations number
17
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
ISSN journal
09514198 → ACNP
Volume
14
Issue
4
Year of publication
2000
Pages
195 - 202
Database
ISI
SICI code
0951-4198(2000)14:4<195:EMITMS>2.0.ZU;2-F
Abstract
Electrospray 'soft' ionisation (ESI) and multistep mass spectrometry (MSn) techniques enable characterisation of a bioactive polymer, poly[(R,S)-3-hyd roxybutanoic acid] (a-PHB), containing covalently bonded benzylpenicillin, The chemical structures of individual mass-selected bioactive macromolecule s have been determined, and their fragmentation mechanisms have been compar ed with those of pure penicillin G, Copyright (C) 2000 John Wiley & Sons, L td.