This study was conducted to develop an equation for the prediction of
outcome in neonatal feats undergoing treatment in an intensive care un
it (ICU). Fifty-three physical examination, historical, and clinicopat
hologic variables were analyzed from the records of 99 neonatal foals
(<14 days of age) treated in the neonatal ICU of the Equine Medical Ce
nter. The outcome was recorded and the results were categorized into e
ither surviving or nonsurviving groups. The mean values for the 2 grou
ps were compared, and variables that differed significantly between th
e two groups were retained and used to construct a logistic regression
equation. Retained variables were heart rate, temperature, and neutro
phil count. The predictive equation then was tested prospectively in 2
additional groups of foals from 2 separate ICUs. The predicted outcom
e was compared to the actual outcome, and performance variables were c
alculated. Sensitivity (.83), specificity (.87), negative predictive v
alue (.72), and positive predictive value (.93) were determined for fo
als from one neonatal ICU; the sensitivity (.83), specificity (.44), n
egative predictive value (.44), and positive predictive value (.83) we
re lower for foals at a second, separate ICU. Copyright (C) 1997 by th
e American College of Veterinary Internal Medicine.