Partition coefficients of adenine, guanine, cytosine and thymine in the poly(ethylene glycol)-K2HPO4-water aqueous two-phase system

Authors
Mishima, K Taruta, Y Ezawa, M Yamauchi, S Ando, S Nishikawa, H
Citation
K. Mishima et al., Partition coefficients of adenine, guanine, cytosine and thymine in the poly(ethylene glycol)-K2HPO4-water aqueous two-phase system, SOL EX R D, 6, 1999, pp. 161-167
Citations number
12
Categorie Soggetti
Chemistry,"Chemical Engineering
Journal title
SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN
ISSN journal
13417215 → ACNP
Volume
6
Year of publication
1999
Pages
161 - 167
Database
ISI
SICI code
1341-7215(1999)6:<161:PCOAGC>2.0.ZU;2-5
Abstract
The partition coefficients of 6-aminopurine(adenine), 2-amino-6-hydroxyprin e(guanine), 4-amino-2-hydroxypyrimidine(cytosine) and 5-metyluracil(thymine ) in the poly(ethylene glycol) 6000(PEG; Avg.M.W.=7,500)(1) -dipotassium hy drogenphosphate (K2HPO4)(2) - water(3) system were determined at 298.15 K, to evaluate the effect of bases composing deoxyribonucleic acid(DNA) on the ir partition coefficients in the aqueous two-phase system. Furthermore, the osmotic virial equation was used to correlate the partition coefficients o f adenine, guanine, cytosine and thymine.