Measurement of the solubilities of flavone and 3-hydroxyflavone in supercritical carbon dioxide by supercritical fluid chromatography

The solubilities of flavone and 3-hydroxyflavone in supercritical carbon di oxide (SC-CO2) were measured at 308.2 K over the pressure range from 9.1 to 25.3 MPa by the degree of retention in supercritical fluid chromatography. Furthermore they were compared with the data obtained by a flow type appar atus. A cell constant, C was determined from solubility parameters. of solu tes estimated by Fedors' method and solubility data of high boiling compoun ds, such as naphthalene and phenanthrene which had already been measured by a flow type apparatus.