Ja. Hamlin et al., RENAL ANGIOMYOLIPOMAS - LONG-TERM FOLLOW-UP OF EMBOLIZATION FOR ACUTEHEMORRHAGE, Canadian Association of Radiologists journal, 48(3), 1997, pp. 191-198
Objective: To determine if elective, angiographically directed emboliz
ation of enlarged renal angiomyolipomas can be used to prevent future
hemorrhagic episodes in patients with tuberous sclerosis and thus avoi
d nephrectomy. Patients and methods: Records were reviewed for all 5 p
atients who underwent elective, subtotal embolization of large, sympto
matic angiomyolipomas at the authors' institution between 1975 and 199
6. Results: All 5 patients had tuberous sclerosis and bilateral renal
angiomyolipomas. Initial embolization in these patients was performed
in 1975, 1981, 1993 (2 patients) and 1994. In 1 patient only a single
embolization session was required. In another, initial embolization on
the left side was followed by embolization on the right 13 months lat
er, Two patients underwent 2 sessions, and 1 patient had 4 sessions ov
er a 13-year period. Subtotal embolization with particulate material l
ed to a decrease in size of the most severely affected portion of the
kidney. One large angiomyolipoma underwent sterile liquefaction after
embolization; percutaneous catheter drainage was required. The emboliz
ation allowed subsequent partial nephrectomy in this patient, Conclusi
on: Embolization is effective for the long-term management of renal an
giomyolipomas in patients with tuberous sclerosis; in this way nephrec
tomy and loss of renal function can usually be avoided.