Mirizzi syndrome is a rare disorder and remains a surgical challenge. It is
generally considered as a contraindication to laparoscopic surgery. Three
patients with Mirizzi type II syndrome and two patients with Mirizzi type I
syndrome were treated laparoscopically. Partial cholecystectomy with fundu
s-first dissection of the gallbladder was performed, and closure of the fis
tula in type II syndrome was achieved over a T-tube. The common bile duct (
CBD) was explored in one patient using a choledochoscope through the fistul
a. The procedure was completed laparoscopically in all five patients. The t
hree patients with type II syndrome had residual CBD stones, which were ass
ociated with significant morbidity and mortality. Laparoscopic treatment of
Mirizzi type I syndrome is technically feasible and safe. For Mirizzi type
II syndrome, laparoscopic CBD exploration is demanding and experience, ski
ll, and the full spectrum of modern technology are required.