Minimally invasive surgery has revolutionized the treatment of gastrointest
inal tumors. Submucosal tumors (SMTs) of the stomach can be resected using
laparoscopic techniques. Between 1993 and 1997, laparoscopic wedge resectio
n was performed in 34 patients with an SMT of the stomach. The tumors range
d from 8 to 60 mm in diameter. All surgical margins were clear. The average
operative time was 131 minutes. Most of the patients began eating on the f
irst postoperative day and were discharged within 5 to 7 days. Histopatholo
gic examination of the tumors showed gastrointestinal stromal tumor (n = 14
), ectopic pancreas (n = 7), leiomyosarcoma (n = 4), schwannoma(n = 3), car
cinoid (n = 2), leiomyoma(n = 2), an inflammatory lesion caused by parasite
s (n = 1), and cyst (n = 1). No recurrences were observed over the 5-year f
ollow-up period. A solid SMT of the stomach larger than 20 mm in diameter c
an be treated using laparoscopic wedge resection.