Clinicofunctional features of arterial hypertension in chronic bronchoobstructive syndrome

Aim. To describe clinicofunctional features of essential and pulmogenic hyp ertension in chronic bronchoobstructive syndrome, 24-h profile of arterial pressure (AP), intracardiac hemodynamics and to propose differential diagno stic criteria for these hypertension forms. Materials and methods. 24-h monitoring of arterial pressure (MAP), cardiohe modynamics, external respiration function (ERF) and blood gases examination s were made in 100 hypertensive subjects with chronic obstructive bronchiti s and bronchial asthma. Results. Significant differences were found between the groups of essential and pulmogenic hypertension by major values of MAP, echo-CG and ERF. Early disturbances in diastolic function of both the ventricles in essential and pulmonary hypertension in chronic bronchial obstruction arise long before clinical, x-ray, and ECC signs of chronic pulmonary heart. Conclusion. The findings enable formulation of criteria of differential dia gnosis of essential and pulmogenic hypertension and identify the latter as an independent nosological entity.