Ahm. Elwahy et Aa. Abbas, Synthesis of new benzo-substituted macrocyclic ligands containing pyridineor triazole as subcyclic units, TETRAHEDRON, 56(6), 2000, pp. 885-895
The macrocyclic diamides 11-21, 42 and 43 were prepared by nucleophilic rea
ction of the bis phenols 22-29 with the appropriate dihalo compounds 2, 3,
40 and 41, respectively. The macrocyclic dithiodiamides 30-33 were obtained
in good yields upon treatment of 11, 13, 15 and 17 with Lawesson's reagent
. The macrocycles 61-63 were prepared by condensation of the bis(aldehyde)
37 with the appropriate bis(aminotriazoles) 50-54 to give the corresponding
Schiff bases 56-60 followed by NaBH4 reduction. (C) 2000 Elsevier Science
Ltd. All rights reserved.