Practical unequivocal synthesis of phosphatidyl-myo-inositols

Authors
Aneja, R Aneja, SG
Citation
R. Aneja et Sg. Aneja, Practical unequivocal synthesis of phosphatidyl-myo-inositols, TETRAHEDR L, 41(6), 2000, pp. 847-850
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
6
Year of publication
2000
Pages
847 - 850
Database
ISI
SICI code
0040-4039(20000205)41:6<847:PUSOP>2.0.ZU;2-A
Abstract
The direct phosphatidylation of 1D-2,3,4,5,6-penta-O-benzyl-myo-inositol wi th sn-3-phosphatidic acid and subsequent hydrogenolytic debenzylation produ ces 1D-1-(sn-3-phosphatidyl)-myo-inositol in excellent yield (>90%) and une quivocal structural and stereochemical purity, and, is readily adaptable fo r large scale production. (C) 2000 Elsevier Science Ltd. All rights reserve d.