Use of iodized salt and risk of iodine excess

Citation
A. Zahidi et al., Use of iodized salt and risk of iodine excess, THERAPIE, 54(5), 1999, pp. 549-552
Citations number
27
Categorie Soggetti
Pharmacology & Toxicology
Journal title
THERAPIE
ISSN journal
00405957 → ACNP
Volume
54
Issue
5
Year of publication
1999
Pages
549 - 552
Database
ISI
SICI code
0040-5957(199909/10)54:5<549:UOISAR>2.0.ZU;2-2
Abstract
Iodine-deficiency disorders are a major problem of public health in Morocco . To mitigate this deficiency, the iodination of all the salt intended for human consumption in a proportion of 80 +/- 10 mg/kg of salt has become obl igatory since a decree published in 1995. We estimated that this rate of io dized salt issued risked inducing an iodine excess in the population. To ch eck this hypothesis, we provided 7 families made up of 28 subjects, who at the start were consuming a non-iodized salt, with the decreed, iodized salt and we followed the evolution of their urinary iodine excretion over a per iod of 3 weeks. The mean values of urinary iodine excretion of the 28 subje cts were 12.8 mu g/dl before use of iodized salt and 26.8, 35.5 and 63.2 mu g/dl, respectively, after 7, 14 and 21 days from the introduction of iodiz ed sale into their diet. After 21 days of the use of iodized salt, 84.6 per cent of the subjects had an iodine excess. We conclude that prolonged use of this iodized salt exposes the population to the risk of thyroid disorder s.