The dynamics of creatinine and urea concentrations in the blood serum of rabbits infected by Encephalitozoon cuniculi microsporidium and treated withalbendazole

Authors
Conkova, E Cellarova, E Neuschl, J Halanova, M Balant, P Sutiak, V
Citation
E. Conkova et al., The dynamics of creatinine and urea concentrations in the blood serum of rabbits infected by Encephalitozoon cuniculi microsporidium and treated withalbendazole, ACT VET BEO, 49(5-6), 1999, pp. 321-326
Citations number
19
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
ACTA VETERINARIA-BEOGRAD
ISSN journal
05678315 → ACNP
Volume
49
Issue
5-6
Year of publication
1999
Pages
321 - 326
Database
ISI
SICI code
0567-8315(1999)49:5-6<321:TDOCAU>2.0.ZU;2-R
Abstract
In this work the concentrations of creatinine and urea in the blood serum o f rabbits infected by Encephalitozoon (E) cuniculi and treated with albenda zole was investigated. A significant decrease in mean creatinine concentrat ion compared to the initial level (day 0) was observed from days 7 to 45. A marked decrease in mean urea concentrations was recorded only on day 60. T he above-mentioned changes in observed biochemical parameters were not clin ically manifested. Albendazole administered twice a week at 5 mg kg(-1) cre ated a sufficiently protective shield for animals from days 7 to 78 of the experiment biochemical parameters were not.