Isolated systolic hypertension and combined systolic and diastolic hyperten
sion are clinical problems affecting significant numbers of older adults (>
65 years). Preventing the complications of hypertension, including stroke a
nd coronary artery disease, may potentially impact not only an individual's
sense of well-being, but also their functional status and ability to live
independently in the community. Despite the increased absolute risk for car
diovascular events associated with hypertension in older adults compared wi
th younger adults, significant numbers of individuals remain untreated or i
nadequately treated. There is clinical data to show that treating bath isol
ated systolic hypertension and combined systolic and diastolic hypertension
results in a significant reduction in cardiovascular events in older adult
s. Although there is a growing body of literature on treatment of hypertens
ion in the 60- to 80-year-old, the data on individuals greater than 80 year
s old is lacking. The challenge becomes to treat hypertension safely in the
presence of multiple medications and other diseases. (C) 2000 by the Natio
nal Kidney Foundation, Inc.