Smoking is not only a risk factor for Crohn's disease, but ongoing smoking
is associated with a poorer disease course. Therefore, smoking cessation sh
ould be an important treatment strategy for Crohn's disease patients who sm
oke tobacco. Recent improvements in understanding how people quit smoking a
nd the development of pharmacological interventions, such as nicotine patch
es and bupropion, have improved cessation rates. In this article, we first
briefly review the evidence supporting the adverse effects of smoking on th
e disease course. We next review the current understanding of how people ch
ange addictive behaviors, such as smoking. We then describe how the gastroe
nterologist can aid the patient with Crohn's disease to quit smoking, inclu
ding appropriate and brief counseling strategies and the use of adjunctive
treatments. Given the improvements in smoking cessation strategies, all pat
ients with Crohn's disease should be strongly advised to quit smoking and b
e aided in doing so. (C) 2000 by Am. Cell. of Gastroenterology.