Managed care organizations would appear to be natural advocates for, and us
ers of, cost-effectiveness analysis (CEA) as a tool for maximizing health o
utcomes for their covered populations within fixed budgets. There is, howev
er, little evidence that CEA plays a major role in managed care decision ma
king. The purpose of this paper is to identify barriers to both conducting
and using CEA in managed care decision making. Lack of understanding about
the value and applicability of CEA, and incentives that do not align with a
lifetime perspective on either health outcomes or costs may be at least as
important as perceived or real methodological limitations of the methodolo
gy. Research focused on ways to overcome these barriers, and thereby improv
e resource allocations, is recommended.