Background. This study was designed to determine if intraoperative atrial a
ctivation mapping facilitates operations for chronic atrial fibrillation as
sociated with mitral valve disease.
Methods. Surgical treatment guided by intraoperative electrophysiologic map
ping was performed in 12 patients with chronic atrial fibrillation associat
ed with isolated mitral valve disease. In 10 of 12 patients, regular and re
petitive activation (cycle length ranged from 118 to 210 msec) originated i
n the left atrial appendage and/or orifice of the left pulmonary vein. In t
he remaining 2 patients, dominant repetitive activation and sporadic comple
x activation were alternately observed in the left atrium. However, the act
ivation sequence of the right atrium was extremely complex and chaotic.
Results. On the basis of intraoperative mapping, surgical procedures, inclu
ding resection of the left atrial appendage and/or cryoablation of the orif
ice of the left pulmonary vein, were applied on the breakthrough site of th
e repetitive activation. No surgical procedure was performed on the right a
trium in II patients. Ten of 12 patients (83%) have maintained sinus rhythm
for 6 to 40 months (average 24.8 months) after operation.
Conclusions. In the majority of the patients with isolated mitral valve dis
ease, the left atrium acts as an electrical driving chamber for chronic atr
ial fibrillation. Computerized intraoperative mapping should guide surgeons
in determining the appropriate surgical procedure for chronic atrial fibri
llation. (C) 2000 by The Society of Thoracic Surgeons.