Capnocytophaga ochracea: Characterization of a plasmid-encoded extended-spectrum TEM-17 beta-lactamase in the phylum Flavobacter-Bacteroides

Authors
Rosenau, A Cattier, B Gousset, N Harriau, P Philippon, A Quentin, R
Citation
A. Rosenau et al., Capnocytophaga ochracea: Characterization of a plasmid-encoded extended-spectrum TEM-17 beta-lactamase in the phylum Flavobacter-Bacteroides, ANTIM AG CH, 44(3), 2000, pp. 760-762
Citations number
22
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
3
Year of publication
2000
Pages
760 - 762
Database
ISI
SICI code
0066-4804(200003)44:3<760:COCOAP>2.0.ZU;2-5
Abstract
A plasmid encoded extended-spectrum TEM beta-lactamase with a pI of 5.5 was detected in a Capnocytophaga ochracea clinical isolate. The bla gene was a ssociated with a strong TEM-2 promoter and was derived from bla(TEM-1a) wit h a single-amino-acid substitution: Glu(104)-->Lys, previously assigned to TEM-17, which is thus the first TEM beta-lactamase to be reported in the ph ylum Flavobacter-Bacteroides.