Captan fungicide exposures of strawberry harvesters using THPI as a urinary biomarker

Citation
Ri. Krieger et Tm. Dinoff, Captan fungicide exposures of strawberry harvesters using THPI as a urinary biomarker, ARCH ENV C, 38(3), 2000, pp. 398-403
Citations number
14
Categorie Soggetti
Environment/Ecology,"Pharmacology & Toxicology
Journal title
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
ISSN journal
00904341 → ACNP
Volume
38
Issue
3
Year of publication
2000
Pages
398 - 403
Database
ISI
SICI code
0090-4341(200004)38:3<398:CFEOSH>2.0.ZU;2-U
Abstract
Clothing affords harvesters considerable protection against the elements an d can retain substantial amounts of pesticide residue from treated crops. N ormal work clothing of female harvesters was supplemented with rubber latex gloves and facial scarves to determine whether those measures reduced expo sure. Captan fungicide exposures in female strawberry harvesters were asses sed by determining urine clearance rates of tetrahydrophalimide (THPI). Cle an rubber gloves were supplied to the 41 harvesters for the 3 days of the s tudy period in October 1995. The workers were divided into two groups consi sting of either bare-handed or gloved workers, and 24-h urine specimens wer e collected each day. Female harvesters who worked bare-handed cleared 5.3 mu g captan equivalents as THPI with a range of 0.4 to 13.8 mu g/person/day . Harvesters who worked wearing rubber latex gloves cleared only 2.0 mu g c aptan equivalents with a range of 0.9 to 4.3 mu g/person/day. In this case clean rubber latex gloves reduced absorbed dose by 38%, compared to the dos e absorbed by bare-handed workers. These results additionally indicate that when a pesticide is avidly retained by rubber latex gloves and not readily absorbed dermally as captan, estimates of absorbed dose based on passive d osimetry data may be less reliable than exposure estimates derived from uri ne biomonitoring.