P. Jais et al., Prospective randomized comparison of irrigated-tip versus conventional-tipcatheters for ablation of common flutter, CIRCULATION, 101(7), 2000, pp. 772-776
Citations number
27
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Background-Radiofrequency (RF) ablation of common flutter requires the crea
tion of a complete ablation line to produce bidirectional conduction block
in the cavotricuspid isthmus. An irrigated-tip ablation catheter has been s
hown to be effective in patients in whom conventional ablation has failed.
This randomized study compares the efficacy and safety of this catheter wit
h those of a conventional catheter for de novo flutter ablation.
Methods and Results-Cavotricuspid ablation was performed with a conventiona
l (n=26) or an irrigated-tip catheter (n=24). RF was applied for 60 minutes
with a temperature-controlled mode: 65 degrees C to 70 degrees C up to 70
W with a conventional catheter or 50 degrees C up to 50 W (with a 17-mL/min
saline flow rate) with the irrigated-tip catheter. The end point was the a
chievement of bidirectional isthmus block, and a crossover was performed af
ter 21 unsuccessful applications. Procedural ablation parameters as well as
number of applications, x-ray exposure, procedure duration, impedance rise
, and clot formation were compared for each group. A coronary angiogram was
performed before and after each ablation for the first 30 patients. Comple
te bidirectional isthmus block was achieved for all patients. Four patients
crossed over from conventional to irrigated-tip catheters. The number of a
pplications, procedure duration, and x-ray exposure were significantly high
er with the conventional than with the irrigated-tip catheter: 13+/-10 vers
us 5+/-3 pulses, 53+/-41 versus 27+/-16 minutes, and 18+/-14 versus 9+/-6 m
inutes, respectively. No significant side effects occurred, and the coronar
y angiograms of the first 30 patients after ablation were unchanged.
Conclusions-Irrigated-tip catheters were found to be more effective than an
d as safe as conventional catheters for flutter ablation, facilitating the
rapid achievement of bidirectional isthmus block.