Bacterial adaptation to host innate immunity responses

Several recent reports show that different bacterial components trigger inn ate and inflammatory responses in host organisms. In parallel, selected bac terial virulence factors have been identified that interfere with correspon ding responses. In many cases, this involves interference with host proinfl ammatory signal transduction pathways, whereas in selected cases bacterial virulence factors interfere with host antibacterial mechanisms. This indica tes that bacteria, besides activating cellular responses, also have the cap acity to directly interact with branches of the innate defence.