Antimicrobial agents have greatly reduced the incidence of intracranial com
plications of infections of the middle ear and mastoid. Too many prescripti
ons and overconsumption of antibiotics when otitis media is suspected has c
aused resistance to many antibiotics, leading to a pronounced and justifiab
le desire to reduce the widespread excessive use of antibiotics. The possib
le untoward consequences of a too restricted antibiotic policy, however, is
illustrated by the following case of a 14-year-old boy who, after non-trea
tment of an ear infection, fell ill with one-sided headache and vomiting ca
used by a lateral sinus thrombosis. After intravenous treatment with antibi
otics, anticoagulants and ventilation of the middle ear, the infection was
cured without complications. This case calls attention to the symptoms of o
titic complications arising outside the temporal bone. The physician must a
lways bear in mind the possibility of an unusual event. The general treatme
nt of endocranial complications is outlined, giving details of the treatmen
t given in this special case. We stress that one should not be too cautious
in prescribing antibiotics in otitis media.