H. Liljeberg et I. Bjorck, Effects of a low-glycaemic index spaghetti meal on glucose tolerance and lipaemia at a subsequent meal in healthy subjects, EUR J CL N, 54(1), 2000, pp. 24-28
Objective: The aim of the study was to evaluate the impact of a low glycaem
ic index (GI) breakfast on glucose tolerance and lipaemia at a subsequent l
unch meal.
Design: A low GI spaghetti meal and a high-GI white wheat bread (WWB) refer
ence meal were served in the morning after an overnight fast in random orde
r. Four hours after the breakfast, the subjects were given a second meal-a
standardized high-GI lunch-and the blood glucose, insulin and lipid respons
es were measured after the lunch meal.
Setting: The study was performed ar the Department of Applied Nutrition and
Food Chemistry, Lund University, Sweden.
Subjects: Ten healthy volunteers, eight women and two men, aged 25-51 y, wi
th normal body mass indices, were recruited.
Results: Lowered glucose and insulin responses and reduced serum triglyceri
de (TG) level were found at the subsequent lunch meal when the low-G1 spagh
etti meal was given as a breakfast. No differences in total serum cholester
ol or HDL cholesterol were seen after lunch. when preceded by the WWB refer
ence breakfast or the spaghetti breakfast, respectively.
Conclusions: Improved glucose tolerance and lowered serum TG levels can app
ear in the course of a single day. As insulin resistance and raised postpra
ndial TG concentration are known risk: factors for cardiovascular disease,
the present study adds evidence for a beneficial role of a low-G1 diet.