Fludarabine-containing regimen followed by autologous peripheral blood stem cell transplantation in unselected patients with acute myeloid leukemia: a single center experience
P. Mazza et al., Fludarabine-containing regimen followed by autologous peripheral blood stem cell transplantation in unselected patients with acute myeloid leukemia: a single center experience, HAEMATOLOG, 85(2), 2000, pp. 222-224
Fludarabine has been recently reported as ineffective in mobilizing periphe
ral blood stem cells (PBSC) in acute myeloid leukemia (AML) patients. We re
port: herein on 27 AML patients, 9 of them being eligible for peripheral bl
ood stem cell transplantation (PBSCT). Eight of the 9 successfully mobilize
d after two courses of a fludarabine-containing regimen and the administrat
ion of CTX at a dose of 4 g/m(2).