Synthesis of RGD peptidomimetic analogues of 2,5-diketopiperazine

Authors
Ramakrishna, NVS More, TS Khandelwal, Y Naik, RG Lal, B Gupte, RD Vadlamudi, RVSV
Citation
Nvs. Ramakrishna et al., Synthesis of RGD peptidomimetic analogues of 2,5-diketopiperazine, I J CHEM B, 38(12), 1999, pp. 1331-1337
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
38
Issue
12
Year of publication
1999
Pages
1331 - 1337
Database
ISI
SICI code
0376-4699(199912)38:12<1331:SORPAO>2.0.ZU;2-O
Abstract
Synthesis of 3-(methylacetate)-6-(N-benzyloxypropylamino)-2,5-diketopiperaz ine 5 and its corresponding RGD analogues 9,11,15 and 16 has been achieved and their platelet aggregation inhibitory activity evaluated.