Although asthma is a disease that has intrigued physicians since antiquity,
its natural history has been incompletely determined. It has long been hel
d that the presence of asthma, per se, does not carry with it any long-term
deterioration in lung function, but recently this view has been challenged
, and it has become fashionable to define asthma as being only partially re
versible, At present, there are limited data to support such a view. All of
the available information indicates that the vast majority of patients do
not experience the development of a progressive decline in pulmonary mechan
ics or appear to be at risk for a diminution in life expectancy.