A potential set up based on histidine hollow fiber membranes for the extracorporeal removal of human antibodies

Authors
Pitiot, O Legallais, C Darnige, L Vijayalakshmi, MA
Citation
O. Pitiot et al., A potential set up based on histidine hollow fiber membranes for the extracorporeal removal of human antibodies, J MEMBR SCI, 166(2), 2000, pp. 221-227
Citations number
19
Categorie Soggetti
Chemistry,"Chemical Engineering
Journal title
JOURNAL OF MEMBRANE SCIENCE
ISSN journal
03767388 → ACNP
Volume
166
Issue
2
Year of publication
2000
Pages
221 - 227
Database
ISI
SICI code
0376-7388(20000301)166:2<221:APSUBO>2.0.ZU;2-R
Abstract
Poly ethylene vinyl alcohol (PEVA) based hollow fiber membrane grafted with L-histidine has been found to be particularly useful for the preparative s cale separation of immunoglobulin G and potential clinical applications. In this paper, we present a set-up designed for the extracorporeal removal of immunoglobulin G. Biochemical and hydrodynamic conditions were optimized s o as to perform in vitro removal of 50% of plasma immunoglobulin G. (C) 200 0 Elsevier Science B.V. All rights reserved.