Isolation of C-dubliniensis from insulin-using diabetes mellitus patients

The identification of the novel candidal species, C. dubliniensis, from ora l swab studies of HIV-seropositive and -seronegative individuals has led to speculation that such a species may also reside in the oral cavity of othe r patient groups. In this study involvement of the newly described species, C. dubliniensis, was investigated in oral carriage and disease in 414 insu lin-using diabetes mellitus patients. Seventy-seven percent of the diabetic patients carried candidal species in the oral cavity. C. albicans was the most commonly identified candidal species. This was followed by C. dublinie nsis, which was isolated on 64 occasions. Colonisation with multiple candid al species was common, and C, dubliniensis was present in both carriage and disease states. Seven patients without signs of oral disease had C. dublin iensis isolated as the sole candidal species, while the same species was as sociated with various forms of oral candidosis in six patients.