Y. Kamijo et al., Pulse steroid therapy in adult respiratory distress syndrome following petroleum naphtha ingestion, J TOX-CLIN, 38(1), 2000, pp. 59-62
Case Report: A suicide attempt by a 23-year-old woman involved ingestion of
1000 mL of petroleum naphtha. Early chemical pneumonitis was complicated b
y life-threatening, diffuse interstitial lung consolidation with pneumatoce
les. Pulse steroid therapy beginning on day 17 was associated with remarkab
le resolution of interstitial consolidation, although an enlarging secondar
ily infected pneumatocele ruptured to produce a bronchopleural fistula. Tho
racic surgery and antibiotic therapy resulted in improvement of the patient
's respiratory condition, and she was discharged with no residual respirato
ry symptoms. High-dose corticosteroid therapy appears to be a useful additi
on to aggressive supportive treatment in late adult respiratory distress sy
ndrome following hydrocarbon ingestion.