Reports of accidental alkaloid-intoxications with plants of the nightshade
family, in particular Datura-species are well known in pediatric care. The
intentional abuse as a hallucinogenic drug in adolescents became more frequ
ent in recent years. Two patients, a 14- resp. 16-year old boy were admitte
d to the intensive care units of our hospitals because of a severe central
anticholinergic syndrome after ingestion of tea from Angel's Trumpet blosso
ms for experimental reasons. Patient's history in the first somnolent patie
nt was not available at the time of admission, a routine immunological drug
screening of the patient's urine had been negative.
Discussion: Prominent central nervous symptoms as unconsciousness or halluc
inations in adolescents without further explanation should suggest a specia
l toxicological analysis for tropan-alcaloids e.g, scopolamine because of i
ncreasing abuse of plants containing the drug.