Chronic ophthalmoplegia with anti-GQ1b antibody

Authors
Reddel, SW Barnett, MH Yan, WX Halmagyi, GM Pollard, JD
Citation
Sw. Reddel et al., Chronic ophthalmoplegia with anti-GQ1b antibody, NEUROLOGY, 54(4), 2000, pp. 1000-1002
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
54
Issue
4
Year of publication
2000
Pages
1000 - 1002
Database
ISI
SICI code
0028-3878(20000222)54:4<1000:COWAA>2.0.ZU;2-E
Abstract
Anti-GQ1b antibodies are typically found in patients with the Miller Fisher syndrome, all of whom will have, by definition, acute ophthalmoplegia. The authors describe three patients with chronic ophthalmoplegia in the presen ce of persistently high titers of immunoglobulin G anti-GQ1b antibody detec ted in an ELISA, one of whom improved with immunotherapy. Anti GQ1b antibod ies may be associated with some cases of chronic ophthalmoplegia of unknown cause.