Radionecrosis of the temporal lobe: dynamic susceptibility contrast MRI

We examined nine patients with histologically proven nasopharyngeal carcino ma (NPC), treated with radiotherapy, using dynamic susceptibility contrast MRI (DSC-MRI). In eight there was clinical evidence of radionecrosis of the temporal lobe, and one was examined for local recurrence in the nasopharyn x. All patients had either high-signal finger-like or cystic lesions in the temporal lobes on T2-weighted images. Heterogeneous contrast enhancement o ccurred in all patients. Relative regional cerebral blood volume (rrCBV) ma pping revealed marked hypoperfusion in all patients. One underwent bilatera l temporal lobectomy and radionecrosis was confirmed histologically.