Thick malignant melanoma is a long-term problem

Citation
Pr. Asquith et al., Thick malignant melanoma is a long-term problem, NZ MED J, 112(1094), 1999, pp. 313-316
Citations number
10
Categorie Soggetti
General & Internal Medicine
Journal title
NEW ZEALAND MEDICAL JOURNAL
ISSN journal
00288446 → ACNP
Volume
112
Issue
1094
Year of publication
1999
Pages
313 - 316
Database
ISI
SICI code
0028-8446(19990827)112:1094<313:TMMIAL>2.0.ZU;2-R
Abstract
Aims. To investigate changes in incidence of in-situ, 'thin' (<0.76 mm) and 'thick' (>0.76 mm) melanoma. To explore the relationship of melanoma depth with the patient's age at diagnosis. Methods. A retrospective case series of melanoma was taken from pathology r ecords in Palmerston North between 1983 and 1994. The denominator populatio n was estimated, for each year, from published 1986 and 1991 census figures . Results. Over the 12 years, the diagnostic rate of in-situ and invasive mel anomas increased annually by 16% and 5%, respectively (Poisson regression, p<0.0001). This analysis did not show a difference between the overall rate of increase in 'thin' and 'thick' invasive melanomas. After excluding Hutc hinson's melanoma, the mean age at diagnosis for 'thin' and 'thick' melanom as was 49.0 and 55.4 years, respectively (p<0.0001); the peak number of 'th in' and 'thick' melanomas were in the 30-39 and 60-69 age groups, respectiv ely. Conclusions. There is evidence for progression from 'thin' to 'thick' melan oma over a 6-to 30-year period. Poor prognosis 'thick' melanomas are curren tly increasing. Providing removal of 'thin' melanomas is sustained, a decli ne in 'thick' melanomas is expected but may take decades.