EVOLUTIONARY RELATIONSHIPS BETWEEN SUGAR KINASES AND TRANSCRIPTIONAL REPRESSORS IN BACTERIA

Authors
TITGEMEYER F REIZER J REIZER A SAIER MH
Citation
F. Titgemeyer et al., EVOLUTIONARY RELATIONSHIPS BETWEEN SUGAR KINASES AND TRANSCRIPTIONAL REPRESSORS IN BACTERIA, Microbiology, 140, 1994, pp. 2349-2354
Citations number
25
Categorie Soggetti
Microbiology
Journal title
Microbiology → ACNP
ISSN journal
13500872
Volume
140
Year of publication
1994
Part
9
Pages
2349 - 2354
Database
ISI
SICI code
1350-0872(1994)140:<2349:ERBSKA>2.0.ZU;2-E
Abstract
We have characterized a new family of proteins (the ROK family) which includes six transcriptional repressors for sugar catabolic operons, t hree sugar kinases, and three unidentified open reading frames. Analys es of the aligned sequences and phylogenetic tree construction allow p redictions regarding the functional nature of conserved domains and re sidues within these proteins as well as the pathway of evolutionary di vergence that gave rise to the family.